BIOL 2421 Microbiology        
Lecture Review Chapters 12 & 13 : Viral Diseases
Dr. Weis

1. Know the major viral family characteristics for the DNA and RNA viruses discussed reagarding:

            a) NA: type, strand [ds, ss], sense [+, -]

            b) Capsid: shape and any unique features

            c) Envelope or “Naked”, spike antigen if important in Dx or Tx

            d) Biosynthesis location

            e) Primary organ system affecting

2. Know the method of attachment and penetration for non-enveloped, enveloped, and special fusion protein enveloped viruses. (See chapter 11 text and notes)

3. Be able to describe a “lytic” vs. “lysogenic” animal viral life cycle.

4. Know four (4) viral virulence factors and how they are used to increase pathogenicity.

5. Know the virus familys and an example of a viral member that can cause various system diseases for the skin, nervous/sensory, respiratory, urinary/reproductive, cardiovascular/lymphatic/immune, and digestive systems.

6. Be able to discuss specific viruses regarding:
            a) Family characteristics (see question #1)

            b) Viral replication (see question #2)

            c) Organ system affecting (see question #5)

            d) Clinical signs/symptoms [those that may be more specific to particular virus]

            e) Diagnosis (Dx)

            f) Treatment (Tx)

            g) Prevention

7. Name four (4) viruses that are important disease causing organisms during prenatal exposure.

8. Know great detail regarding HIV (see question 6, plus add reservoir, transmission, special membrane surface antigens, genetic code, etc.)

9. Define: latent, naked virion, transmission: direct, indirect, horizontal, vertical; vector,

mortality, morbidity.

10. Name four (4) viruses that may be associated with the oncogenic theory of disease.