Pathophysiology Lecture Review: Immune System

1. Define immunity, name the two MAJOR divisions and explain how they defend the body.
2. Define inflammation. Name two chemicals involved. Name four clinical signs of acute inflammation. List 5 diseases that have a chronic inflammatory component.
3. Name the lymphocytes responsible for cancer surveillance.
4. Name two interleukins and one other cytokine and give their function.
5. Name the three end results when complement is activated.
6. Name the antibody classes and their location.
7. Define antigen and haptan.  Give the possible end results when antibody binds to antigen
8. Explain the source and function of perforin.
9. Explain MHC and its importance in organ transplants.  Give two clinical sign of an organ transplant failure.
10. Name the four types of hypersensitivities and explain the mechanism for each. Give a specific example of each of these types of reactions.
11. Name a primary immunodeficiency disease and describe its etiology and treatment.
12. Name a secondary immunodeficiency disease and describe its etiology and treatment.
13. What is amyloidosis and where can this process occur?
14. Name three autoimmune diseases and explain their etiologies.  Give a possible treatment or therapy for these autoimmune diseases.
15. Name a genetic disease that results in an immune disease or condition.